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St. Catherine Creek National Wildlife Refuge headquarters is located 13 miles south of Natchez, Mississippi. From Natchez, follow U.S. Highway 61 South approximately 10 miles to Sibley. Turn right and follow York Road 2 miles to the refuge entrance. Turn left on Pintail Lane. The headquarters is located approximately 0.7 miles down Pintail Lane on the right. Refuge directional signs are located at each turn.
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